The perioperative nursing care of a child with type Ⅲ gaucher disease with severe kyphosis is summarized. Nursing points include preoperative multidisciplinary collaborative diagnosis and treatment,adequate preoperative preparation,prevention of neurological damage,implementation of individualized rapid plans,postoperative care for paralytic intestinal obstruction,infection prevention,safety management,and psychological health of children and their families. After active treatment and meticulous care by the medical team,the child was discharged 18 days later. After 1 year of following up,he is in good condition and has returned to the normal school and family life.